Functional Medicine Archives | Natural Women's Health Institute https://naturalwomenshealthinstitute.com/category/functional-medicine/ Dr. Caroline Peterson Sun, 07 Jul 2024 19:55:44 +0000 en-US hourly 1 Histamine, Depression, and Inflammation https://naturalwomenshealthinstitute.com/2024/07/07/histamine-depression-and-inflammation/ https://naturalwomenshealthinstitute.com/2024/07/07/histamine-depression-and-inflammation/#respond Sun, 07 Jul 2024 19:10:31 +0000 https://naturalwomenshealthinstitute.com/?p=3624 What Is Histamine? Histamine is a neurotransmitter that is made out of the amino acid called histadine. It affects many processes in the body including Autonomic function Energy/Arousal/Sleep Digestion Body Temperature Cognition Immune system Histamine Has 5 Receptors H1 =Airways, blood vessels, skin, heart etc H2 =Gastric mucosa H3 = Central nervous system [...]

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What Is Histamine?

Histamine is a neurotransmitter that is made out of the amino acid called histadine.

It affects many processes in the body including

  • Autonomic function
  • Energy/Arousal/Sleep
  • Digestion
  • Body Temperature
  • Cognition
  • Immune system

Histamine Has 5 Receptors

  • H1 =Airways, blood vessels, skin, heart etc
  • H2 =Gastric mucosa
  • H3 = Central nervous system and other neurotransmitters
  • H4 = Bone marrow

Histamine Is Broken Down By Two Pathways

  • DAO – Diamino Oxidase – in the gut
  • HNMT – Histamine-N-Methyltransferase – in the cell (50-80% of all histamine metabolism)

Food is only associated with about 5% of all the histamine in your body

That said, a low FODMAPS diet can still be super helpful for people with IBS and decrease gut mast cell activation.

To do a low histamine diet stay away from old food like fermented food, alcohol, dried fruit, aged cheese, processed meat, dried beans

Also stay away from foods that have sugars in them that can break down too easily and become old like garlic, onion, cruciferous vege, some nuts, some grains

How Does Histamine Relate to Depression?

H3 Histamine receptors regulate serotonin transport to ensure there is enough serotonin in the synapse.

Histamine kind of works like and SSRI in the central nervous system, but without the side effects.

H3 Histamine receptors also influence serotonin release.

Histamine and serotonin levels are inverse to each other. High histamine means low serotonin. So working to optimize histamine can also optimize serotonin.

Inflammation and Depression

Inflammation and depression are comorbid.
That means they occur together.

If you are inflamed you will have high levels of histamine and lower levels of serotonin.

If you have inflammation and high histamine, histamine will induce a breach of the blood brain barrier that will lead to more brain inflammation and affective disorders, foggy brain, and cognitive decline.

H1R – Histamine receptors 1 – in the prefrontal cortex and the frontal cortex and the cingulate gyrus are associated with depression

H3R – Histamine receptors 3 – hyperpolarize serotonin neurons and inhibit serotonin signalling. This can also be a pathway leading to depression

Mast Cell Function

Mast cells are messengers between the nervous system and the immune system.

They are associated with activation of pain fibers and transmission

Mast cells are a major producer of histamine and histamine provokes increased estrogen production.

Mast Cells Are Regulated by

  • Vagus nerve
  • Acetylcholine (parasympathetic neurotransmitter)
  • Nitric oxide

Mast Cell Activation Syndrome (MCAS)

  • Standard Allergy Symptoms (rash, itch, runny nose, sneeze etc)
  • Pelvic pain/endometriosis/vulvodynia
  • Bladder pain/overactive bladder
  • Anxiety/depression
  • Difficulty sleeping
  • Fatigue
  • Palpitations
  • Constipation/diarrhea

Mast Cells and Estrogen

Mast cells have estrogen receptors, and high estrogen can cause mast cell degranulation.

Estradiol increases the number of mast cells

Dural mast cells are associated with menstrual migraines

Estrogen can decrease DAO

Endocrine disruptors like BPA (Bisphenol A) can bind to estrogen sites and activate a mast cell response.

Mast Cells and Progesterone

Mast cells also have progesterone receptors.

But progesterone can either help to stabilize mast cells, or induce histamine release.

Vitamin D & Short Chain Fatty Acids Also Stabilize Mast Cells

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What Expectations Should I Have For Care? https://naturalwomenshealthinstitute.com/2023/07/07/what-expectations-should-i-have-for-care/ https://naturalwomenshealthinstitute.com/2023/07/07/what-expectations-should-i-have-for-care/#respond Fri, 07 Jul 2023 22:55:00 +0000 https://naturalwomenshealthinstitute.com/?p=3541 It is important that you come to care with right-sized expectations. Let me begin by saying I am not a magician. You have had health care problems for years, or decades, and have sought help from many people. You are disappointed and frustrated because you have tried very hard for a very long time [...]

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It is important that you come to care with right-sized expectations.

Let me begin by saying I am not a magician.

You have had health care problems for years, or decades, and have sought help from many people.

You are disappointed and frustrated because you have tried very hard for a very long time to find health.

This health history shows me two things:

1) You are valient

2) You have a complex case that does not respond well to traditional intervention.

I want to help you, but also, I see that because you are a complex case, it will take time to work you up and figure out what is going on.

You probably have multiple systems involved and multiple conditions.

We can figure this out, but it will take more than 1 day.

With complex cases like yours, we need to have a global approach.

Generally complex cases take 20 hours of manual therapy and 5 hours of internal medicine.

If we go too fast, you could have a healing crisis called a herxheimer reaction or “herxing”.

That means you have exceeded your metabolic capacity and your detoxification system’s competence for removing toxins.

A herxing response does not mean the treatment is bad.

It means the treatment is going too fast for your body, or that your body needs additional support.

Be patient with yourself as you heal.

We can go at a speed that is right for you and your body.

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How To Do Resistance Breathing and Why https://naturalwomenshealthinstitute.com/2023/06/02/how-to-do-resistance-breathing-and-why/ https://naturalwomenshealthinstitute.com/2023/06/02/how-to-do-resistance-breathing-and-why/#respond Fri, 02 Jun 2023 10:00:59 +0000 https://naturalwomenshealthinstitute.com/?p=3496 Only 30 breaths a day can change your life! Although the benefits of resistance breathing are not new knowledge, COVID lung has brought the practice to the fore. Resistance breath training improves lung function, cardiovascular function, and autonomic function. Resistance breathing also correctly activates the transverse planes (diaphragms) of the body and the core [...]

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Only 30 breaths a day can change your life!

Although the benefits of resistance breathing are not new knowledge, COVID lung has brought the practice to the fore. Resistance breath training improves lung function, cardiovascular function, and autonomic function. Resistance breathing also correctly activates the transverse planes (diaphragms) of the body and the core muscles so you are able to drain your fluid body more optimally and optimize musculoskeletal and organ function.

Only 5 minutes a day of resistance breathing can improve

  • blood pressure
  • blood vessel tone
  • oxygen saturation
  • pulse rate
  • respiration rate
  • lung capacity
  • obstructive sleep apnea
  • exercise duration
  • inflammation

What is resistance breath training?

Resistance breath training involves breathing into and out of a little pipe that costs about $50. You can turn a knob and set the degree of resistance for in and out breaths. The resistance of the pipe forces the chest respiratory muscles to activate properly, and also properly activates the core musculature that is involved in creating a canister required for optimal breathing.

Resistance breathing forces you to breathe correctly. When you breathe correctly the muscles move properly, endothelial nitric oxide is released, the lungs fill and empty properly, and circulation improves.

The research shows that only five minutes of resistance breathing a day is as good as going to the gym for lowering your blood pressure.

TIP: Do both

Here is an example of the pipe. Not all pipes have in and out resistance. This one has both.

https://www.amazon.com/Breather-Inspiratory-Expiratory-Respiratory-Trainer/dp/B00FE8N7Y4

The app and instructions for this pipe do not cohere with physiologic breathing practices. Please follow the instructions in this protocol so you can implement physiologic breathing.

How to do resistance breath training

  • Brush your teeth or at least rinse out your mouth
  • Set your resistance breathing device at the highest number for inhale and for exhale resistance
  • Position the device in your mouth and breathe in and out only through your mouth
  • Use the highest setting for a couple breaths so you can feel the muscles fire automatically
  • Decrease the resistance to a level you can continue for 30 breaths
  • Breathe in for three seconds
  • Breathe out for seven seconds
  • Repeat these slow breaths for five minutes.
  • Practice resistance breathing most days
  • Practice resistance breathing if you feel anxious and it will quickly put you into parasympathetic dominance so you feel more at ease

If you get tired, dizzy, can’t catch your breath or have a racing heart STOP

Wait until the next day and try again with less resistance or faster breaths or shorter duration of treatment.

Slow resistance breathing is physiologic breathing

Our bodies are designed to breathe six times every minute. For optimal autonomic tone we should breathe in for three seconds (stimulating the sympathetic nervous system) and out for seven seconds (stimulating the parasympathetic nervous system).

We are designed to be strong. When our core muscles are strong, with the ribcage they act as a canister for breathing, and our body itself offers resistance to the breath. Because most of us do not have strong enough core muscles or intercostal muscles (between the ribs) we are not able to practice resistance breathing without the aid of a device.

Normal physiologic breathing fills the lungs from bottom to top. As the lungs fill, the ribcage expands two inches circumferentially. There is no elevation of the ribcage becasue the transversus abdominus is holding the ribcage down toward the pelvis. After the ribcage has maximally expanded, the lungs push the respiratory diaphragm down and the belly resists the displacement of the organs as the pelvic diaphragm also lowers.

When we breathe out the respiratory diaphragm and pelvic diaphragm elevate and the abdomen and chest shrink circumferentially two inches.

Using the device for resistance breathing helps us to strengthen and optimize our own canister so that long term we will not need the device, but will be strong enough in ourselves to provide proper resistance for breathing.

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Welcome New Patients! https://naturalwomenshealthinstitute.com/2023/02/13/welcome-new-patients/ https://naturalwomenshealthinstitute.com/2023/02/13/welcome-new-patients/#respond Mon, 13 Feb 2023 16:17:13 +0000 https://naturalwomenshealthinstitute.com/?p=2914 Welcome New Patients! This video introduces you to my practice and my orientation for your care.

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Conditions Treated & Good-Fit Patient https://naturalwomenshealthinstitute.com/2023/02/04/good-fit-patient/ https://naturalwomenshealthinstitute.com/2023/02/04/good-fit-patient/#respond Sat, 04 Feb 2023 20:50:40 +0000 https://naturalwomenshealthinstitute.com/?p=2476 You are a seeker, game to explore the complexity of the self and the body.

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My practice focuses on

  • women’s reproductive health
  • infertility
  • pelvic pain
  • organ prolapse
  • post-partum rehabilitation
  • incontinence
  • pain that has not responded to chiropractic, acupuncture, and massage
  • venous congestion or varicosities
  • bladder dysfunction
  • bowel dysfunction

My approach combines

  • visceral manipulation
  • vascular manipulation
  • myofascial release
  • lymphatic drainage
  • holistic pelvic care
  • craniosacral therapy
  • functional medicine
  • chiropractic medicine
  • energy medicine
  • mind-body therapy emotional work

My Good-Fit Patient

  • someone who is curious about their being (body-mind-spirit) and wants to integrate and explore as they heal
  • someone who uses whatever pain or dysfunction they experience as a guide to help them on their journey of self-discovery
  • someone who is excited to work on the physical, chemical, emotional, and energetic body for complex transformation that invites coming into a whole new phase of life

Welcome!

I am your ally as we journey together.

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